Protein in human umbilical cord blood rejuvenates old mice's impaired learning, memory. The lead author is former postdoctoral scholar Joseph Castellano, PhD, who is now an instructor of neurology and neurological sciences. To distinguish the effects of old, young and "youngest" human blood on hippocampal function, the researchers used immune-deficient laboratory mice that could be given repeated injections of human plasma without experiencing negative immune reactions. The table is also full of holes, one of which is attached to a tube in which a scared mouse can find darkness and safety. And older mice's performance on the Barnes maze and other tests was stellar in comparison with mice of the same age who got injections of saline instead of plasma. But older mice that were given human cord plasma depleted of TIMP2 derived no learning and memory benefits. "TIMP2's effects in the brain have been studied a little, but not much and not in aging," said Castellano. "In our study, it mimicked the memory and learning effects we were getting with cord plasma. And it appeared to do that by improving hippocampal function." Human umbilical cord plasma proteins revitalize hippocampal function in aged mice.
If worrying about life in retirement is keeping you up at night, here’s a suggestion: Curl up with a good book on personal finance.
Researchers in Japan have found that people who scored higher on a test for financial literacy were less likely to report feeling anxious about what their retirement years had in store for them. The study was published online April 13, 2017, in the Journal of Risk Research.
The researchers analyzed data from a large, nationwide survey in Japan. As part of the survey, men and women were asked whether they had “anxieties” about what life would be like for them after age 65. For this study, the researchers focused on respondents over age 40, on the theory that middle age is when most people begin to think seriously, and fret, about later life.
Survey respondents also answered four questions to assess their financial literacy. Two involved basic money math, including this one:
Q. Imagine that the interest rate on your savings account was 1 percent per year and inflation was…